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Filtered Search Results
Selleck Chemical LLC RK-33
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RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest induces apoptosis and promotes radiation sensitization in DDX3-overexpressing cells
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Medchemexpress LLC Acid Ceramidase-IN-2 | 1005497-03-9 | C30H47NO6 | 1 MG
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Acid Ceramidase-IN-2 is an acid ceramidase inhibitor with potential antiproliferative and cytostatic activities. Human acid ceramidase is overexpressed in prostate cancer cells, suggesting a potential anti-tumor effect. Its hydrolysis can be inhibited in vitro by 3 α-ketoamides: GT85, GT98, and GT99.
- Potential antiproliferative and cytostatic activities
- Inhibits human acid ceramidase, which is overexpressed in prostate cancer cells
- Hydrolysis inhibited by 3 α-ketoamides: GT85, GT98, and GT99
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Selleck Chemical LLC 2-Aminoethylphosphonic acid S3331-5mg
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2-Aminoethylphosphonic acid (2-AEP (2-Aminoethyl)phosphonic acid) is a type of abundant and ubiquitous naturally occurring phosphonate used as sources of phosphorus by many prokaryotic lineages
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Selleck Chemical LLC ML-297
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ML-297 (VU 0456810 CID 56642816) is a potent and selective activator of Kir3 1/3 2 (G protein-coupled inwardly rectifying potassium GIRK1/2) channel with EC50 of 0 16 M and 1 8 M for GIRK1/2 and GIRK1/4 respectively ML-297 is potential for the treatment of epilepsy
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Cell Signaling Technology Phospho-CREB (Ser133) (1B6) Mouse mAb 20 ul
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Phospho-CREB (Ser133) (1B6) Mouse mAb 20 ul
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Sigma Aldrich Fine Chemicals Biosciences T37i Mouse Brown Adipocyte
Brown adipose tissue (brown fat) has generated intense research interest due to its unique thermogenic properties and potential applications for development of treatments for metabolic diseases (1). Cellular models that reliably reflect the transition of preadipocytes to brown fat are necessary tools for investigating the mechanisms and roles of brown fat in metabolic systems.The T37i cell line is a rapidly proliferating brown preadipocyte cell line derived from a mouse hibernoma. Differentiation of T37i cells into brown adipocytes occurs when incubated with triiodothyronine (T3) and insulin over 3-6 days. Differentiation can also be induced by incubation with steroid hormones such as aldosterone which induces differentiation through its interaction with mineralocorticoid receptor (MR). Mature brown adipocytes are characterized via triglyceride accumulation morphology and expression of early adipogenic genes (2). Differentiated T37i cells express the thermogenic uncoupling protein 1
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Promega Corporation MAXPREP LIQUID HANDLER
PRAS9105 MAXPREP LIQUID HANDLER
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Medchemexpress LLC TA 0910 acid-type 50mg | 103300-77-2 | 406.39 g·mol⁻¹ | C17H22N6O6 | 50 MG
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TA 0910 acid-type is a small-molecule metabolite of a metabolically stable thyrotropin releasing hormone (TRH) analogue. Supplied as a solid for research use, the product is characterized by high purity, defined storage conditions, and solubility guidance for in vitro applications.
- High purity: 99.85%
- Appearance: white to off-white solid
- Molecular formula: C17H22N6O6
- Molecular weight: 406.39 g·mol⁻¹
- Solubility: DMSO up to 25 mg/mL with ultrasonic warming
- Storage: powder -20°C (3 years) or 4°C (2 years)
- Intended use: for research use only
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Cayman Chemical 2 4Dichlorophenoxy Acetic Aci
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A synthetic auxin used as a supplement in plant cell culture media; an active ingredient in herbicides that controls root elongation and cell production by disrupting the actin cytoskeleton
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Cayman Chemical AS 115 Inhibitors
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A single enantiomer of a potent and selective inactivator of KIAA1363, a MAGE hydrolase an enzyme that is upregulated in aggressive cancers from various tissues (IC50 = 150 nM when tested as a racemic mixture in SK0V-3 cells); activity of the individual enantiomers of AS 115, i.e,. (+)-AS 115 and (−)-AS 115, has not been determined
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Selleck Chemical LLC Tiaprofenic acid
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Tiaprofenic acid (Tiaprofensaeure Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain especially arthritic pain
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Selleck Chemical LLC MRT68921 HCl
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MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2 9 nM and 1 1 nM respectively
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Apexbio Technology LLC Folinic acid 58-05-9 50mg
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Folinic acid (CAS 58-05-9) also known as leucovorin is a biologically active form of folate present in cellular folate pools typically comprising 10 20% of total folate content Functioning as a cofactor in one-carbon transfer reactions folinic acid bypasses dihydrofolate reductase inhibition to restore nucleotide synthesis In experimental models it mitigates methotrexate-induced chromosomal damage and acts as an anticlastogenic agent by reducing cytogenetic abnormalities Folinic acid is frequently utilized in research as a rescue agent to counteract methotrexate cytotoxicity and to modulate the effects of antifolate chemotherapy agents
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eMolecules J W PharmLab LLC 3 3-Difluoro-cyclobutanone 250mg 525281684 10R0594 96 000 1273564-99-0 MFCD18791190 106 072 C4H4F2O
J W PharmLab LLC 3 3-Difluoro-cyclobutanone 250mg 525281684 10R0594 96 000 1273564-99-0 MFCD18791190 106 072 C4H4F2O
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Sigma Aldrich Fine Chemicals Biosciences Dapagliflozin 98 HPLC5MG
DAPAGLIFLOZIN804 Dapagliflozin 98 HPLC5MG
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